Abhayrab is a vaccine used to prevent rabies after exposure (after contact with a rabid or suspected rabid animal). For profylactic immunization of all high-risk individuals such as veterinarians, municipal workers, medical and paramedical personnel and zoo personnel, hunters, laboratory personnel, working with suspected rabies materials and pet owners. Dosage/Direction PRE-EXPOSURE PROPHYLAXIS (prior to exposure) Intradermal (ID) Regimen 0.1 mL at one site only (Adults: deltoid area of the arm, Children: anterolateral area of the thigh acceptable) on days 0, 7, and 21/28. Intramuscular (IM) Regimen: 1 vial of 0.5 mL PVRV at on site only (Adults: deltoid area of the arm, Children: anterolateral area of the thigh acceptable) on days 0, 7, and 21/28. Booster Doses: One booster dose should be given every one to three (1-3) years depending on risks of exposure. POST-EXPOSURE TREATMENT (after exposure): Intramuscular Schedule: One dose is equivalent to 1 vial of 0.5 mL of Abhayrab. To be given either as 5-dose IM regimen (1 dose on days 0,3,7,14 and 28) OR as 2-1-1 regimen (2 doses are given on day 0 in the deltoid or anterolateral region, right and left side. In addition, 1 dose in the deltoid or anterolateral region, right or left side). Intradermal Schedule: One dose is equivalent to 0.1 mL of Abhayrab WHO recommended the following intradermal regimen for post-exposure immunization: Thai Red Cross (TRC) 2-2-2-0-1-1 regimen: One dose is given over each left and right deltoid on days 0,3,7. One dose at single site in deltoid on day 28/30 and day 90. Updated TRC regimen (2-2-2-0-2): Day 90 dose has been transferred to day 28/30. One dose is given over each deltoid on days 0,3,7 and 28/30.
