Description Panadol Extra with Optizorb contains a clinically proven combination of medicinal ingredients. Each caplet contains paracetamol and caffeine, with advanced Optizorb technology. Panadol Extra with Optizorb is designed to fight five types of tough pain: migraine headache, period pain, tension headache, muscle aches and pains, and dental pain/toothache. Get tough on tough pain. Choose Panadol Extra with Optizorb Caplets for relief of tough pain. Panadol Extra with Optizorb (pain relief caplets) doesn?t contain ibuprofen, gluten, lactose or sugar.